Acute Myeloid Leukemia and the Bone Marrow Niche—Take a Closer Look

Acute Myeloid Leukemia and the Bone Marrow Niche—Take a Closer Look

The bone marrow is the home of hematopoiesis and is therefore a hotspot for the development of hematopoietic diseases. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells must find a balance between proliferation, differentiation and homeostasis of the stem cel...

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Bibliographic Details
Main Authors: Lena Behrmann, Jasmin Wellbrock, Walter Fiedler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
acute myeloid leukemia
AML
bone marrow
angiogenesis
niche
endothelial cell
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00444/full

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