Chapter 15: disease gene prioritization.

Disease-causing aberrations in the normal function of a gene define that gene as a disease gene. Proving a causal link between a gene and a disease experimentally is expensive and time-consuming. Comprehensive prioritization of candidate genes prior to experimental testing drastically reduces the as...

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Bibliographic Details
Main Author: Yana Bromberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23633938/pdf/?tool=EBI