Elevated DNA methylation in malignant tumors of the sinonasal tract and its association with patient survival

Elevated DNA methylation in malignant tumors of the sinonasal tract and its association with patient survival

Background: Epigenetic modifications have been recognized as an important mechanism underlying carcinoma progression. DNA methylation plays an important role in cancer biology and represents potentially heritable changes in gene expression that do not involve DNA sequence. The aim of this study was...

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Bibliographic Details
Main Authors: Marcela Chmelarova, Jan Laco, Helena Kovarikova, Ivana Baranova, Pavel Dundr, Kristyna Nemejcova, Jaroslav Michalek, Milan Vosmik, Vladimir Palicka
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2018-09-01
Series:Biomedical Papers
Subjects:
biomarkers
dna methylation
sinonasal carcinoma
epigenetics
Online Access:https://biomed.papers.upol.cz/artkey/bio-201803-0011_elevated_dna_methylation_in_malignant_tumors_of_the_sinonasal_tract_and_its_association_with_patient_survival.php

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