Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.

Recognition of specific cell surface glycans, mediated by the VP8* domain of the spike protein VP4, is the essential first step in rotavirus (RV) infection. Due to lack of direct structural information of virus-ligand interactions, the molecular basis of ligand-controlled host ranges of the major hu...

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Bibliographic Details
Main Authors: Yang Liu, Shenyuan Xu, Andrew L Woodruff, Ming Xia, Ming Tan, Michael A Kennedy, Xi Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5705156?pdf=render