Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells

Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells

Effects and mechanisms of kaempferol, identified in a wide variety of dietary sources, on the expression of interleukin (IL)-6, IL-8, matrix metallo proteinase (MMP)-1, and cyclooxygenase (COX)-2 were evaluated in IL-1β-induced SW982 cells. The cells were pretreated with kaempferol of various concen...

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Bibliographic Details
Main Authors: Jun-Jiang Lian, Bin-Feng Cheng, Yao-Xin Gao, Han Xue, Lei Wang, Mian Wang, Hai-Jie Yang, Zhi-Wei Feng
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Functional Foods
Subjects:
Kaempferol
Inflammatory mediator
Signalling pathway
SW982 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616302791

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