Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants

Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants

The recent pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has raised global health concerns. The viral 3-chymotrypsin-like cysteine protease (3CLpro) enzyme controls coronavirus replication and is essential for its life cycle. 3CLpro is a proven drug discovery target in the cas...

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Bibliographic Details
Main Authors: Muhammad Tahir ul Qamar, Safar M. Alqahtani, Mubarak A. Alamri, Ling-Ling Chen
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Coronavirus
SARS-CoV-2
COVID-19
Natural products
Protein homology modelling
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920301271

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http://www.sciencedirect.com/science/article/pii/S2095177920301271

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