Seroprevalence and clinical correlates of human immunodeficiency virus infection among women with infertility in northwestern Nigeria

• Main Authors: Anisah Yahya, Adebiyi Adesiyun, Fatima Giwa, Abdulhakeem A Olorukooba
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Tropical Journal of Obstetrics and Gynaecology
• Subjects: Clinical correlates; human immunodeficiency virus infection; infertility.
• Online Access: http://www.tjogonline.com/article.asp?issn=0189-5117;year=2018;volume=35;issue=2;spage=177;epage=183;aulast=Yahya

Background: Infertility is a major cause of social and psychological problems among couples, especially in our environment where child bearing is regarded as one of the major reasons for marriage. Studies have shown that fertility among human immunodeficiency virus (HIV)-infected women may actually be reduced posing social and psychological disturbance among a group of people that are already burdened with disease. Objective: The aim of the study was to determine the prevalence and clinical correlates of HIV infection among women with infertility attending a gynecology clinic in northwestern Nigeria. Materials and Methods: It was a cross-sectional descriptive study comprising of women attending the gynecology clinic due to infertility that satisfied the inclusion criteria. The sample size was 250. Ethical clearance was obtained from the health research and ethics committee of the study setting. Clients were recruited consecutively as they presented to the infertility clinic from May 2015 to January 2016 and tested for HIV infection. HIV testing was done in the Department of Medical Microbiology after collecting 5 ml of blood from the clients using sterile syringes. Investigations to determine the cause of infertility were also conducted. Obtained data were analyzed using Statistical Package for Social Science version 20.0. Results: A total of 250 clients were recruited for the study. The age range of respondents was- 17 – 47 years with a mean age of 30.3 years. Hausa was the predominant ethnic group in all respondents (61%). Most of the respondents had secondary education (39%). Only 4% had postgraduate education. Out of the 250 respondents, 21 (8.4%) were found to be positive for HIV infection. Chi-square test showed an association between tuboperitoneal infertility and HIV infection. Conclusion: The prevalence of HIV infection in women with infertility attending our clinic was high and an association was seen between HIV infection and tuboperitoneal infertility.