Myosin VI and Associated Proteins Are Expressed in Human Macrophages but Do Not Play a Role in Foam Cell Formation in THP-1 Cells

Myosin VI (Myo6) functions in endocytosis in conjunction with binding partners including adaptor protein (AP)-2, disabled 2 (Dab2), and GAIP interacting protein C terminus 1 (GIPC1). This study aimed to investigate the expression and function of Myo6 in macrophages and its possible role in the endoc...

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Bibliographic Details
Main Authors: Hayley J. Dawson, Andrew P. Hibbert, Peter D. Chantler, Kathleen M. Botham
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2013/516015