Synthesis and X-Ray Crystal Structure of (1E)-1-(4-Chlorophenyl)-N-hydroxy-3-(1H-imidazol-1-yl)propan-1-imine
Synthesis and characterization of (1E)-1-(4-chlorophenyl)-N-hydroxy-3-(1H-imidazol-1-yl)propan-1-imine (4) are reported. X-ray crystal structure of the title oxime 4 confirmed its assigned (E)-configuration. The compound crystallizes in the monoclinic space group P21/c with a=13.4292 (3) Å, b=8.8343...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/418601 |
| Summary: | Synthesis and characterization of (1E)-1-(4-chlorophenyl)-N-hydroxy-3-(1H-imidazol-1-yl)propan-1-imine (4) are reported. X-ray crystal structure of the title oxime 4 confirmed its assigned (E)-configuration. The compound crystallizes in the monoclinic space group P21/c with a=13.4292 (3) Å, b=8.8343 (2) Å, c=11.1797 (3) Å, α=90°, β=108.873 (2)°, γ=90°, V=1255.03 (5) Å3, and Z=4. The molecules are packed in crystal structure by weak intermolecular O–H⋯N hydrogen bonding interactions. Compound 4 is a useful intermediate for the synthesis of new imidazole-containing antifungal agents. |
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| ISSN: | 2090-9063 2090-9071 |