<it>In vitro</it> silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells

<it>In vitro</it> silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells

<p>Abstract</p> <p>Background</p> <p>Insulin receptor (InsR) and insulin signaling proteins are widely distributed throughout the kidney cortex. Insulin signaling can act in the kidney in multiple ways, some of which may be totally independent of its primary role of the...

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Bibliographic Details
Main Authors: Yano Naohiro, Suzuki Daisuke, Endoh Masayuki, Zhang Weizhi, Xu Yan, Padbury James F, Tseng Yi-Tang
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Cell Communication and Signaling
Subjects:
Insulin receptor
Fibronectin
Mesangial cells
CREB-1
MMP-9
Online Access:http://www.biosignaling.com/content/10/1/29

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