Effect of advanced blood pressure control with nifedipine delayedrelease tablets on the blood pressure in patients underwent nasal endoscope surgery
Objective: To explore the effect of advanced blood pressure control with nifedipine delayedrelease tablets on the blood pressure in patients underwent nasal endoscope surgery and its feasibility. Methods: A total of 80 patients who were admitted in ENT department from June, 2012 to June, 2015 for...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2016-08-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/201616/44.pdf |
| Summary: | Objective: To explore the effect of advanced blood pressure control with nifedipine delayedrelease tablets on the blood pressure in patients underwent nasal endoscope surgery and its
feasibility. Methods: A total of 80 patients who were admitted in ENT department from June,
2012 to June, 2015 for nasal endoscope surgery were included in the study and randomized
into the observation group and the control group with 40 cases in each group. The patients
in the observation group were given nifedipine delayed-release tablets for advanced blood
pressure control before operation, and were given routine blood pressure control during
operation; while the patients in the control group were only given blood pressure control
during operation. The changes of blood pressure, mean central arterial pressure, and heart rate
before anesthesia (T0), after intubation (T1), during operation (T2), extubation when waking
(T3), 30 min after extubation (T4), and 3 h after back to wards (T5) in the two groups were
compared. The intraoperative situation and the surgical field quality in the two groups were
compared. Results: SBP, DBP, and MAP levels at T1-5 in the two groups were significantly
lower than those at T0. SBP, DBP, and MAP levels at T2 were significantly lower than those at
other timing points, and were gradually recovered after operation, but were significantly lower
than those at T0. The effect taking time of blood pressure reducing, intraoperative nitroglycerin
dosage, and postoperative wound surface exudation amount in the observation group were
significantly less than those in the control group. The surgical field quality scores in the
observation group were significantly superior to those in the control group. Conclusions:
Advanced blood pressure control with nifedipine delayed-release tablets can stabilize the blood
pressure during the perioperative period in patients underwent nasal endoscope surgery, and
enhance the surgical field qualities. |
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| ISSN: | 1007-1237 1007-1237 |