A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis

A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis

A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.

Bibliographic Details
Main Authors: Palakodety Radha Krishna, Krishnarao Lopinti, K. L. N. Reddy
Format: Article
Language:English
Published: Beilstein-Institut 2009-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Carreira asymmetric alkynylation
Cryptocarya bourdilloni GAMB (Lauraceae)
ring-closing metathesis
Sharpless asymmetric epoxidation
Online Access:https://doi.org/10.3762/bjoc.5.14
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spelling doaj-96896de9c84949cebd4f5dc1888765442021-02-02T01:38:42ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972009-04-01511410.3762/bjoc.5.141860-5397-5-14A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesisPalakodety Radha Krishna0Krishnarao Lopinti1K. L. N. Reddy2D-206/B, Discovery Laboratory, Organic Chemistry Division-III, Indian Institute of Chemical Technology, Hyderabad-500 607, India, Fax: +91-40-27160387D-206/B, Discovery Laboratory, Organic Chemistry Division-III, Indian Institute of Chemical Technology, Hyderabad-500 607, India, Fax: +91-40-27160387Government Degree College, Khairatabad, Hyderabad-500 004A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.https://doi.org/10.3762/bjoc.5.14Carreira asymmetric alkynylationCryptocarya bourdilloni GAMB (Lauraceae)ring-closing metathesisSharpless asymmetric epoxidation
collection DOAJ
language English
format Article
sources DOAJ
author Palakodety Radha Krishna
Krishnarao Lopinti
K. L. N. Reddy
spellingShingle Palakodety Radha Krishna
Krishnarao Lopinti
K. L. N. Reddy
A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
Beilstein Journal of Organic Chemistry
Carreira asymmetric alkynylation
Cryptocarya bourdilloni GAMB (Lauraceae)
ring-closing metathesis
Sharpless asymmetric epoxidation
author_facet Palakodety Radha Krishna
Krishnarao Lopinti
K. L. N. Reddy
author_sort Palakodety Radha Krishna
title A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_short A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_full A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_fullStr A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_full_unstemmed A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_sort short stereoselective synthesis of (+)-(6r,2′s)-cryptocaryalactone via ring-closing metathesis
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2009-04-01
description A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.
topic Carreira asymmetric alkynylation
Cryptocarya bourdilloni GAMB (Lauraceae)
ring-closing metathesis
Sharpless asymmetric epoxidation
url https://doi.org/10.3762/bjoc.5.14
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AT krishnaraolopinti ashortstereoselectivesynthesisof6r2scryptocaryalactoneviaringclosingmetathesis
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