Histidine protects against zinc and nickel toxicity in Caenorhabditis elegans.

Histidine protects against zinc and nickel toxicity in Caenorhabditis elegans.

Zinc is an essential trace element involved in a wide range of biological processes and human diseases. Zinc excess is deleterious, and animals require mechanisms to protect against zinc toxicity. To identify genes that modulate zinc tolerance, we performed a forward genetic screen for Caenorhabditi...

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Bibliographic Details
Main Authors: John T Murphy, Janelle J Bruinsma, Daniel L Schneider, Sara Collier, James Guthrie, Asif Chinwalla, J David Robertson, Elaine R Mardis, Kerry Kornfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3063764?pdf=render

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