Dna2 processes behind the fork long ssDNA flaps generated by Pif1 and replication-dependent strand displacement
DNA2 encodes a 5′ flap DNA endonuclease involved in replication and DNA double strand break processing. Here the authors by using a conditional degron system together with electron microscopy characterize the role played by Dna2 and Pif1 helicase during unperturbed DNA replication in S. cerevisiae....
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07378-5 |