TOR regulates cell death induced by telomere dysfunction in budding yeast.

Telomere dysfunction is known to induce growth arrest (senescence) and cell death. However, the regulation of the senescence-death process is poorly understood. Here using a yeast dysfunctional telomere model cdc13-1, which carries a temperature sensitive-mutant telomere binding protein Cdc13p, we d...

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Bibliographic Details
Main Authors: Haiyan Qi, Yongjie Chen, Xuan Fu, Chao-Po Lin, X F Steven Zheng, Leroy F Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2567032?pdf=render