Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry

Objective. By comparing the differences in microcirculatory responses of the heart and lung meridians induced by moxibustion on these two meridians, respectively, this study aimed to investigate the specificity for site-to-site association on body surface between different meridians. Methods. Eighty...

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Main Authors: Yongliang Jiang, Hantong Hu, Xiaoyu Li, Jiali Lou, Yajun Zhang, Xiaofen He, Yuanyuan Wu, Xiaomei Shao, Jianqiao Fang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2021/6644625
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spelling doaj-9672bf3150424fa8a2bd8e2fb4eb45912021-04-12T01:24:17ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-42882021-01-01202110.1155/2021/6644625Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler FlowmetryYongliang Jiang0Hantong Hu1Xiaoyu Li2Jiali Lou3Yajun Zhang4Xiaofen He5Yuanyuan Wu6Xiaomei Shao7Jianqiao Fang8Department of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchDepartment of Neurobiology and Acupuncture ResearchObjective. By comparing the differences in microcirculatory responses of the heart and lung meridians induced by moxibustion on these two meridians, respectively, this study aimed to investigate the specificity for site-to-site association on body surface between different meridians. Methods. Eighty healthy adults were enrolled and divided into the lung meridian intervention group and heart meridian intervention group in a ratio of 1 : 1. Three-channel laser Doppler flowmetry was used to monitor microcirculatory responses for the heart and lung meridians. Primary outcome was change of blood perfusion units (PU) of three measurement sites along the two meridians. Results. In the lung meridian intervention group, following moxibustion performed at LU5 of the lung meridian, PU in the distal site of the lung meridian increased significantly. By contrast, the PU of HT3 in the heart meridian, which was nearest to the moxibustion site, did not change significantly. PU in the distal site of the heart meridian declined. Meanwhile, significant difference in PU change was detected between the distal site of the lung meridian and the other two control sites of the heart meridians during moxibustion and postmoxibustion. Alternatively, similar to the results of the lung meridian intervention group, the specificity of microcirculatory response between the heart and lung meridians was observed in the heart meridian intervention group. Conclusions. For the heart and lung meridians, the effect of moxibustion-induced microcirculatory response may be more related to meridian routes than the specific distance between two sites located at different meridians, thereby supporting possible specificity for site-to-site association on the body surface between these two meridians. Nevertheless, given that only two meridians and limited measurement sites were compared, all current findings are not sufficiently robust. Further research should be conducted to investigate more meridians and measurement sites.http://dx.doi.org/10.1155/2021/6644625
collection DOAJ
language English
format Article
sources DOAJ
author Yongliang Jiang
Hantong Hu
Xiaoyu Li
Jiali Lou
Yajun Zhang
Xiaofen He
Yuanyuan Wu
Xiaomei Shao
Jianqiao Fang
spellingShingle Yongliang Jiang
Hantong Hu
Xiaoyu Li
Jiali Lou
Yajun Zhang
Xiaofen He
Yuanyuan Wu
Xiaomei Shao
Jianqiao Fang
Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
Evidence-Based Complementary and Alternative Medicine
author_facet Yongliang Jiang
Hantong Hu
Xiaoyu Li
Jiali Lou
Yajun Zhang
Xiaofen He
Yuanyuan Wu
Xiaomei Shao
Jianqiao Fang
author_sort Yongliang Jiang
title Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
title_short Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
title_full Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
title_fullStr Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
title_full_unstemmed Difference in Moxibustion-Induced Microcirculatory Responses between the Heart and Lung Meridians Assessed by Laser Doppler Flowmetry
title_sort difference in moxibustion-induced microcirculatory responses between the heart and lung meridians assessed by laser doppler flowmetry
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-4288
publishDate 2021-01-01
description Objective. By comparing the differences in microcirculatory responses of the heart and lung meridians induced by moxibustion on these two meridians, respectively, this study aimed to investigate the specificity for site-to-site association on body surface between different meridians. Methods. Eighty healthy adults were enrolled and divided into the lung meridian intervention group and heart meridian intervention group in a ratio of 1 : 1. Three-channel laser Doppler flowmetry was used to monitor microcirculatory responses for the heart and lung meridians. Primary outcome was change of blood perfusion units (PU) of three measurement sites along the two meridians. Results. In the lung meridian intervention group, following moxibustion performed at LU5 of the lung meridian, PU in the distal site of the lung meridian increased significantly. By contrast, the PU of HT3 in the heart meridian, which was nearest to the moxibustion site, did not change significantly. PU in the distal site of the heart meridian declined. Meanwhile, significant difference in PU change was detected between the distal site of the lung meridian and the other two control sites of the heart meridians during moxibustion and postmoxibustion. Alternatively, similar to the results of the lung meridian intervention group, the specificity of microcirculatory response between the heart and lung meridians was observed in the heart meridian intervention group. Conclusions. For the heart and lung meridians, the effect of moxibustion-induced microcirculatory response may be more related to meridian routes than the specific distance between two sites located at different meridians, thereby supporting possible specificity for site-to-site association on the body surface between these two meridians. Nevertheless, given that only two meridians and limited measurement sites were compared, all current findings are not sufficiently robust. Further research should be conducted to investigate more meridians and measurement sites.
url http://dx.doi.org/10.1155/2021/6644625
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