Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells.

Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells.

Understanding the dynamic relationship between components of a system or pathway at the individual cell level is a current challenge. To address this, we developed an approach that allows simultaneous tracking of several endogenous proteins of choice within individual living human cells. The approac...

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Bibliographic Details
Main Authors: Irina Issaeva, Ariel A Cohen, Eran Eden, Cellina Cohen-Saidon, Tamar Danon, Lydia Cohen, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958823?pdf=render

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