Repeated Low-Level Blast Overpressure Leads to Endovascular Disruption and Alterations in TDP-43 and Piezo2 in a Rat Model of Blast TBI

Repeated Low-Level Blast Overpressure Leads to Endovascular Disruption and Alterations in TDP-43 and Piezo2 in a Rat Model of Blast TBI

Recent evidence linking repeated low-level blast overpressure exposure in operational and training environments with neurocognitive decline, neuroinflammation, and neurodegenerative processes has prompted concern over the cumulative deleterious effects of repeated blast exposure on the brains of ser...

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Bibliographic Details
Main Authors: Lanier Heyburn, Rania Abutarboush, Samantha Goodrich, Rodrigo Urioste, Andrew Batuure, Jonathan Statz, Donna Wilder, Stephen T. Ahlers, Joseph B. Long, Venkata Siva Sai Sujith Sajja
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neurology
Subjects:
blast-induced neurotrauma
blood-brain barrier
Piezo2
TDP-43
low-level blast
training relevant
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00766/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.00766/full

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