Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems

Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.

Bibliographic Details
Main Authors: Ashot Papikian, Wanlu Liu, Javier Gallego-Bartolomé, Steven E. Jacobsen
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08736-7
Description
Summary:Few approaches for targeted manipulation of the epigenome are available in plants. Here, the authors adapt the dCas9-SunTag system to engineer targeted gene activation and site-specific manipulation of DNA methylation in Arabidopsis.
ISSN:2041-1723