Phemindole, a synthetic di-indole derivative maneuvers the store operated calcium entry (SOCE) to induce potent anti-carcinogenic activity in human triple negative breast cancer cells

Phemindole, a synthetic di-indole derivative maneuvers the store operated calcium entry (SOCE) to induce potent anti-carcinogenic activity in human triple negative breast cancer cells

Triple-negative breast cancer (TNBC), is a specific subtype of epithelial breast tumours that are immuno-histochemically negative for the protein expression of the estrogen receptor (ER), the progesterone receptor (PR) and lack over expression/gene amplification of HER2. This subtype of breast cance...

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Bibliographic Details
Main Authors: Supriya eChakraborty, Swatilekha eGhosh, Bhaswati eBanerjee, Abhishek eSantra, Arghya eAdhikary, Anup K Misra, Parimal C Sen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Pharmacology
Subjects:
Store-operated calcium entry (SOCE)
triple negative breast cancer (TNBC)
Phemindole
Stromal interaction molecule1 (STIM1)
Human Breast carcinoma MDAMB-231 cells.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00114/full

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