Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a key component of the DNA-PK complex that has a well-characterized function in the non-homologous end-joining repair of DNA double-strand breaks. Since its identification, a large body of evidence has demonstrated that DNA-PKcs is fre...

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Bibliographic Details
Main Authors: Haitang Yang, Feng Yao, Thomas M. Marti, Ralph A. Schmid, Ren-Wang Peng
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3389