Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory
Laboratory mice develop populations of circulating memory CD4+ T cells in the absence of overt infection. We have previously shown that these populations are replenished from naive precursors at high levels throughout life (Gossel et al., 2017). However, the nature, relative importance and timing of...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48901 |