Significance of the Tks4 scaffold protein in bone tissue homeostasis

Significance of the Tks4 scaffold protein in bone tissue homeostasis

Abstract The main driver of osteoporosis is an imbalance between bone resorption and formation. The pathogenesis of osteoporosis has also been connected to genetic alterations in key osteogenic factors and dysfunction of bone marrow mesenchymal stem/stromal cells (BM-MSCs). Tks4 (encoded by the Sh3p...

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Main Authors: Virag Vas, Tamás Kovács, Szandra Körmendi, Andrea Bródy, Gyöngyi Kudlik, Bálint Szeder, Diána Mező, Dóra Kállai, Kitti Koprivanacz, Balázs L. Merő, Metta Dülk, József Tóvári, Péter Vajdovich, Ş. Neslihan Şenel, Ilknur Özcan, Zsuzsanna Helyes, Csaba Dobó-Nagy, László Buday
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-42250-6

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