The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors.

Over the last 2 decades, several coronaviruses (CoVs) have crossed the species barrier into humans, causing highly prevalent and severe respiratory diseases, often with fatal outcomes. CoVs are a large group of enveloped, single-stranded, positive-sense RNA viruses, which encode large replicase poly...

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Bibliographic Details
Main Authors: Anja Pišlar, Ana Mitrović, Jerica Sabotič, Urša Pečar Fonović, Milica Perišić Nanut, Tanja Jakoš, Emanuela Senjor, Janko Kos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009013