Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter

Borrelia burgdorferi is an extreme amino acid (AA) auxotroph whose genome encodes few free AA transporters and an elaborate oligopeptide transport system (B. burgdorferi Opp [BbOpp]). BbOpp consists of five oligopeptide-binding proteins (OBPs), two heterodimeric permeases, and a heterodimeric nucleo...

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Bibliographic Details
Main Authors: Ashley M. Groshong, Abhishek Dey, Irina Bezsonova, Melissa J. Caimano, Justin D. Radolf, Steven J. Projan
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e02047-17