Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands.

The extracellular matrix (ECM) is abnormal in breast tumors and has been reported to contribute to breast tumor progression. One factor, which may drive ongoing matrix synthesis in breast tumors, is the loss of stromal caveolin-1 (cav-1), a scaffolding protein of caveolae, which has been linked to b...

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Bibliographic Details
Main Authors: Christopher Thompson, Sahar Rahim, Jeremiah Arnold, Abigail Hielscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5302825?pdf=render