Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.

It has become generally accepted that new neurones are added and integrated mainly in two areas of the mammalian CNS, the subventricular zone and the subgranular zone (SGZ) of the dentate gyrus (DG) of the hippocampus, which is of central importance in learning and memory. The newly generated cells...

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Bibliographic Details
Main Authors: José J Rodríguez, Victoria C Jones, Masashi Tabuchi, Stuart M Allan, Elysse M Knight, Frank M LaFerla, Salvatore Oddo, Alexei Verkhratsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2492828?pdf=render