Late-stage trifluoromethylthiolation of benzylic C-H bonds
Fluoroalkylation of C-H bonds is a class of reaction highly sought after in medicinal chemistry. Here, the authors report a regioselective organophotoredox-catalyzed, trifluoromethylthiolation of benzylic C-H bonds for a wide variety of alkyl (hetero)arenes, and demonstrate its utility in continuous...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12844-9 |