C-Reactive Protein-Based Strategy to Reduce Antibiotic Dosing for the Treatment of Pneumococcal Infection

C-Reactive Protein-Based Strategy to Reduce Antibiotic Dosing for the Treatment of Pneumococcal Infection

C-reactive protein (CRP) is a component of innate immunity. The concentration of CRP in serum increases in microbial infections including Streptococcus pneumoniae infection. Employing a mouse model of pneumococcal infection, it has been shown that passively administered human wild-type CRP protects...

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Bibliographic Details
Main Authors: Donald N. Ngwa, Sanjay K. Singh, Alok Agrawal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
C-reactive protein
clarithromycin
pneumococcal infection
Streptococcus pneumoniae
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.620784/full

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