JC virus mediates invasion and migration in colorectal metastasis.
INTRODUCTION:JC Virus (JCV), a human polyomavirus, is frequently present in colorectal cancers (CRCs). JCV large T-Ag (T-Ag) expressed in approximately half of all CRC's, however, its functional role in CRC is poorly understood. We hypothesized that JCV T-Ag may mediate metastasis in CRC cells...
Main Authors: | Alexander Link, Sung Kwan Shin, Takeshi Nagasaka, Francesc Balaguer, Minoru Koi, Barbara Jung, C Richard Boland, Ajay Goel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2781631?pdf=render |
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