SUPERVISED MACHINE LEARNING MODEL FOR MICRORNA EXPRESSION DATA IN CANCER

• Main Authors: Indra Waspada, Adi Wibowo, Noel Segura Meraz
• Format: Article
• Language: English
• Published: Universitas Indonesia 2017-06-01
• Series: Jurnal Ilmu Komputer dan Informasi
• Subjects: Cancer, MicroRNA, classification, Decesion Tree, Naïve Bayes, Neural Network, Deep Learning
• Online Access: http://jiki.cs.ui.ac.id/index.php/jiki/article/view/481

The cancer cell gene expression data in general has a very large feature and requires analysis to find out which genes are strongly influencing the specific disease for diagnosis and drug discovery. In this paper several methods of supervised learning (decisien tree, naïve bayes, neural network, and deep learning) are used to classify cancer cells based on the expression of the microRNA gene to obtain the best method that can be used for gene analysis. In this study there is no optimization and tuning of the algorithm to test the ability of general algorithms. There are 1881 features of microRNA gene epresi on 25 cancer classes based on tissue location. A simple feature selection method is used to test the comparison of the algorithm. Expreriments were conducted with various scenarios to test the accuracy of the classification.