Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

Abstract Background The protective effect of melatonin against bone metabolism imbalance in osteoporosis (OP) induced by drugs such as retinoic acid (RA) is unclear. The aim of this study was to explore the role of melatonin in bone destruction based on a mouse model. Methods RA-induced OP model mic...

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Bibliographic Details
Main Authors: Xudong Wang, Tongzhou Liang, Yuanxin Zhu, Jincheng Qiu, Xianjian Qiu, Chengjie Lian, Bo Gao, Yan Peng, Anjing Liang, Hang Zhou, Xiaoming Yang, Zhiheng Liao, Yongyong Li, Caixia Xu, Peiqiang Su, Dongsheng Huang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Molecular Medicine
Subjects:
Osteoporosis
Melatonin
Bone metabolism
Bone remodeling
Oxidant stress
Online Access:http://link.springer.com/article/10.1186/s10020-019-0107-0

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