Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection

Caspase-3 controls the apoptotic pathway, a form of programmed cell death designed to be immunologically silent. Polymorphisms leading to reduced caspase-3 activity are associated with variable effects on tumorigenesis and yet arise frequently. Staphylococcus aureus is a human commensal and a freque...

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Bibliographic Details
Main Authors: Volker Winstel, Olaf Schneewind, Dominique Missiakas
Format: Article
Language:English
Published: American Society for Microbiology 2019-11-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.02270-19