<i>Dnmt3b</i> Deficiency in Myf5<sup>+</sup>-Brown Fat Precursor Cells Promotes Obesity in Female Mice

<i>Dnmt3b</i> Deficiency in Myf5<sup>+</sup>-Brown Fat Precursor Cells Promotes Obesity in Female Mice

Increasing energy expenditure through activation of brown fat thermogenesis is a promising therapeutic strategy for the treatment of obesity. Epigenetic regulation has emerged as a key player in regulating brown fat development and thermogenic program. Here, we aimed to study the role of DNA methylt...

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Bibliographic Details
Main Authors: Shirong Wang, Qiang Cao, Xin Cui, Jia Jing, Fenfen Li, Huidong Shi, Bingzhong Xue, Hang Shi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
Dnmt3b
epigenetics
brown adipocytes
thermogenesis
obesity
Online Access:https://www.mdpi.com/2218-273X/11/8/1087

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