The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases

The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases

Small molecules containing quinone and/or oxime moieties have been found as promising anti-fungal agents. One of them is 4-AN, a recently reported potent anti-Candida compound, which inhibits the formation of hyphae, decreases the level of cellular phosphoproteome, and finally shows no toxicity towa...

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Bibliographic Details
Main Authors: Maciej Masłyk, Monika Janeczko, Aleksandra Martyna, Sławomir Czernik, Małgorzata Tokarska-Rodak, Marta Chwedczuk, Béatrice Foll-Josselin, Sandrine Ruchaud, Stéphane Bach, Oleg M. Demchuk, Konrad Kubiński
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
Candida albicans
arylcyanomethylenequinones
4-AN
protein kinases
antifungal agent
atomic force microscopy
Online Access:http://www.mdpi.com/1420-3049/24/1/153

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