Theta-Defensins Inhibit High-Risk Human Papillomavirus Infection Through Charge-Driven Capsid Clustering

Theta-Defensins Inhibit High-Risk Human Papillomavirus Infection Through Charge-Driven Capsid Clustering

Persistent infection with high-risk human papillomavirus (hrHPV) genotypes results in a large number of anogenital and head and neck cancers worldwide. Although prophylactic vaccination coverage has improved, there remains a need to develop methods that inhibit viral transmission toward preventing t...

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Bibliographic Details
Main Authors: Joseph G. Skeate, Wouter H. Segerink, Mauricio D. Garcia, Daniel J. Fernandez, Ruben Prins, Kim P. Lühen, Féline O. Voss, Diane M. Da Silva, W. Martin Kast
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
human papillomavirus
alpha-defensins
theta-defensins
infection
innate-immunology
sexually transmitted infection (STI)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.561843/full

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