Pruritus and Atopic Dermatitis: from Etiological Features to Management

Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was co...

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Main Authors:	Nikolay N. Murashkin, Leonid A. Opryatin, Roman V. Epishev, Alexander I. Materikin, Eduard T. Ambarchian, Roman A. Ivanov, Dmitriy V. Fedorov, Daria S. Kukoleva
Format:	Article
Language:	English
Published:	"Paediatrician" Publishers LLC 2020-12-01
Series:	Voprosy Sovremennoj Pediatrii
Subjects:	pruritus atopic dermatitis skin barrier dermocosmetics emollient plus
Online Access:	https://vsp.spr-journal.ru/jour/article/view/2508

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spelling	doaj-95ea216c4ddc440d95667b7c82e63da32021-07-28T21:15:47Zeng"Paediatrician" Publishers LLC Voprosy Sovremennoj Pediatrii1682-55271682-55352020-12-0119646847610.15690/vsp.v19i6.21511916Pruritus and Atopic Dermatitis: from Etiological Features to ManagementNikolay N. Murashkin0Leonid A. Opryatin1Roman V. Epishev2Alexander I. Materikin3Eduard T. Ambarchian4Roman A. Ivanov5Dmitriy V. Fedorov6Daria S. Kukoleva7National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs; Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”National Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthPruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.https://vsp.spr-journal.ru/jour/article/view/2508pruritusatopic dermatitisskin barrierdermocosmeticsemollient plus
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nikolay N. Murashkin Leonid A. Opryatin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchian Roman A. Ivanov Dmitriy V. Fedorov Daria S. Kukoleva
spellingShingle	Nikolay N. Murashkin Leonid A. Opryatin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchian Roman A. Ivanov Dmitriy V. Fedorov Daria S. Kukoleva Pruritus and Atopic Dermatitis: from Etiological Features to Management Voprosy Sovremennoj Pediatrii pruritus atopic dermatitis skin barrier dermocosmetics emollient plus
author_facet	Nikolay N. Murashkin Leonid A. Opryatin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchian Roman A. Ivanov Dmitriy V. Fedorov Daria S. Kukoleva
author_sort	Nikolay N. Murashkin
title	Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_short	Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_full	Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_fullStr	Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_full_unstemmed	Pruritus and Atopic Dermatitis: from Etiological Features to Management
title_sort	pruritus and atopic dermatitis: from etiological features to management
publisher	"Paediatrician" Publishers LLC
series	Voprosy Sovremennoj Pediatrii
issn	1682-5527 1682-5535
publishDate	2020-12-01
description	Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.
topic	pruritus atopic dermatitis skin barrier dermocosmetics emollient plus
url	https://vsp.spr-journal.ru/jour/article/view/2508
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Pruritus and Atopic Dermatitis: from Etiological Features to Management

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