From the lab to the people: major challenges in the biological treatment of Down syndrome<br /> Running title: Biological treatment of Down syndrome

Down syndrome (DS) refers to a genetic condition due to the triplication of human chromosome 21. It is the most frequent autosomal trisomy. In recent years, experimental work has been conducted with the aim of removing or silencing the extra chromosome 21 (C21) in cells and normalizing genetic expre...

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Bibliographic Details
Main Author: Jean A Rondal
Format: Article
Language:English
Published: AIMS Press 2021-02-01
Series:AIMS Neuroscience
Subjects:
Online Access:http://www.aimspress.com/article/doi/10.3934/Neuroscience.2021015?viewType=HTML