White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation

White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation

Obesity is associated with white adipose tissue (WAT) hypoxia and inflammation. We aimed to test whether mild environmental oxygen restriction (OxR, 13% O<sub>2</sub>), imposing tissue hypoxia, triggers WAT inflammation in obese mice. Thirteen weeks diet-induced obese male adult C57BL/6J...

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Bibliographic Details
Main Authors: Femke P. M. Hoevenaars, Jaap Keijer, Inge van der Stelt, Loes P. M. Duivenvoorde, Laure Herreman, Robin van Nes, David Friedecký, Maria A. Hegeman, Evert M. van Schothorst
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Genes
Subjects:
hypoxia
whole genome microarray gene expression
cholecystokinin
white adipose tissue
inflammation
adipokine
Online Access:https://www.mdpi.com/2073-4425/10/5/359

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