Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years

BackgroundRadiotherapy treatment after keloidectomy is known to be an effective method for reducing the rate of recurrence. However, to date, the appropriate total radiation dose and fractionation have not yet been confirmed. The authors performed a retrospective analysis to identify the appropriate...

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Main Authors: Kyuhee Kim, Daegu Son, Jinhee Kim
Format: Article
Language:English
Published: Korean Society of Plastic and Reconstructive Surgeons 2015-09-01
Series:Archives of Plastic Surgery
Subjects:
Ear
Online Access:http://www.e-aps.org/upload/pdf/aps-42-588.pdf
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spelling doaj-95de0ace235b48119d111b19fe3e6f7b2020-11-24T23:23:21ZengKorean Society of Plastic and Reconstructive SurgeonsArchives of Plastic Surgery2234-61632234-61712015-09-0142558859510.5999/aps.2015.42.5.588564Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 YearsKyuhee Kim0Daegu Son1Jinhee Kim2Department of Plastic and Reconstructive Surgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.Department of Plastic and Reconstructive Surgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.Department of Radiation Oncology, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.BackgroundRadiotherapy treatment after keloidectomy is known to be an effective method for reducing the rate of recurrence. However, to date, the appropriate total radiation dose and fractionation have not yet been confirmed. The authors performed a retrospective analysis to identify the appropriate radiation dose and fractionation in post-keloidectomy radiotherapy.MethodsFrom May 2000 to February 2011, postoperative radiotherapy was performed on 39 lesions in 28 patients after total keloidectomy. The keloid lesions were confined to the ear lobes. Between May 2000 and May 2004, 14 keloids were treated with surgical excision, followed by a total radiation dose of 1,200 cGy in three fractions over four to five days (group 1). Between June 2004 to February 2011, 25 keloids were treated with surgical excision, followed by a total radiation dose of 1,500 cGy in three fractions over four to five days (group 2). Patients were given a survey asking them to report their experiences regarding reoperation, recurrence of symptoms, recurrence of the lesion, and satisfaction with the operation.ResultsOf the 28 patients who were treated, 20 underwent follow-up. Group 2 had more cases showing elevation with erythematous changes, whereas group 1 had more cases showing progressive stages of elevation than group 2. These differences were statistically significant. Moreover, a correlation was observed between the level of keloid elevation and the extent of symptoms.ConclusionsWe suggest 1,500 cGy of radiation in three fractions following keloidectomy for ear lobe keloids. A further randomized study is needed to assess the recurrence of keloids after radiotherapy.http://www.e-aps.org/upload/pdf/aps-42-588.pdfKeloidRadiationEar
collection DOAJ
language English
format Article
sources DOAJ
author Kyuhee Kim
Daegu Son
Jinhee Kim
spellingShingle Kyuhee Kim
Daegu Son
Jinhee Kim
Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
Archives of Plastic Surgery
Keloid
Radiation
Ear
author_facet Kyuhee Kim
Daegu Son
Jinhee Kim
author_sort Kyuhee Kim
title Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
title_short Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
title_full Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
title_fullStr Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
title_full_unstemmed Radiation Therapy Following Total Keloidectomy: A Retrospective Study over 11 Years
title_sort radiation therapy following total keloidectomy: a retrospective study over 11 years
publisher Korean Society of Plastic and Reconstructive Surgeons
series Archives of Plastic Surgery
issn 2234-6163
2234-6171
publishDate 2015-09-01
description BackgroundRadiotherapy treatment after keloidectomy is known to be an effective method for reducing the rate of recurrence. However, to date, the appropriate total radiation dose and fractionation have not yet been confirmed. The authors performed a retrospective analysis to identify the appropriate radiation dose and fractionation in post-keloidectomy radiotherapy.MethodsFrom May 2000 to February 2011, postoperative radiotherapy was performed on 39 lesions in 28 patients after total keloidectomy. The keloid lesions were confined to the ear lobes. Between May 2000 and May 2004, 14 keloids were treated with surgical excision, followed by a total radiation dose of 1,200 cGy in three fractions over four to five days (group 1). Between June 2004 to February 2011, 25 keloids were treated with surgical excision, followed by a total radiation dose of 1,500 cGy in three fractions over four to five days (group 2). Patients were given a survey asking them to report their experiences regarding reoperation, recurrence of symptoms, recurrence of the lesion, and satisfaction with the operation.ResultsOf the 28 patients who were treated, 20 underwent follow-up. Group 2 had more cases showing elevation with erythematous changes, whereas group 1 had more cases showing progressive stages of elevation than group 2. These differences were statistically significant. Moreover, a correlation was observed between the level of keloid elevation and the extent of symptoms.ConclusionsWe suggest 1,500 cGy of radiation in three fractions following keloidectomy for ear lobe keloids. A further randomized study is needed to assess the recurrence of keloids after radiotherapy.
topic Keloid
Radiation
Ear
url http://www.e-aps.org/upload/pdf/aps-42-588.pdf
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AT daeguson radiationtherapyfollowingtotalkeloidectomyaretrospectivestudyover11years
AT jinheekim radiationtherapyfollowingtotalkeloidectomyaretrospectivestudyover11years
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