Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78.

Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78.

Endoplasmic reticulum (ER) stress occurs as a result of accumulation of unfolded or misfolded proteins in the ER and is involved in the mechanisms of various diseases, such as cancer and neurodegeneration. The goal of the present study was to clarify the relationship between ER stress and pathologic...

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Bibliographic Details
Main Authors: Shinsuke Nakamura, Haruka Takizawa, Masamitsu Shimazawa, Yuhei Hashimoto, Sou Sugitani, Kazuhiro Tsuruma, Hideaki Hara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609792?pdf=render

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