Inorganic arsenic trioxide induces gap junction loss in association with the downregulation of connexin43 and E-cadherin in rat hepatic “stem-like” cells

Chronic exposure to inorganic arsenic trioxide causes tumors of the skin, urinary bladder, lung, and liver. Several cancer initiators and promoters have been shown to alter cell–cell signaling by interference with gap junction intercellular communication (GJIC) and/or modulation of cell adhesion mol...

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Bibliographic Details
Main Authors: Pi-Jung Hsiao, Jo-Chi Jao, Jin-Lian Tsai, Wen-Tsan Chang, Kuo-Shyang Jeng, Kung-Kai Kuo
Format: Article
Language:English
Published: Wiley 2014-02-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X13002660