Cloning and Overexpression of the Toy Cluster for Titer Improvement of Toyocamycin in Streptomyces diastatochromogenes

Cloning and Overexpression of the Toy Cluster for Titer Improvement of Toyocamycin in Streptomyces diastatochromogenes

The nucleoside antibiotic toyocamycin (TM) is a potential fungicide that can control plant diseases, and it has become an attractive target for research. Streptomyces diastatochromogenes 1628, a TM-producing strain, was isolated by our laboratory and was considered to be a potent industrial producer...

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Bibliographic Details
Main Authors: Zheng Ma, Yefeng Hu, Zhijun Liao, Jie Xu, Xianhao Xu, Andreas Bechthold, Xiaoping Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
toyocamycin
Streptomyces diastatochromogenes 1628
cluster
heterologous expression
overproduction
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.02074/full

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