Two N-Linked Glycans Differentially Control Maturation, Trafficking and Proteolysis, but not Activity of the IL-11 Receptor

Two N-Linked Glycans Differentially Control Maturation, Trafficking and Proteolysis, but not Activity of the IL-11 Receptor

Background/Aims: The cytokine interleukin-11 (IL-11) has important pro- and anti-inflammatory functions. It activates its target cells through binding to the IL-11 receptor (IL-11R), and the IL-11/IL-11R complex recruits a homodimer of glycoprotein 130 (gp130). N-linked glycosylation, a post-transla...

Full description

Bibliographic Details
Main Authors: Maria Agthe, Yvonne Garbers, Joachim Grötzinger, Christoph Garbers
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
IL-11
IL-11R
Gp130
Glycosylation
Online Access:https://www.karger.com/Article/FullText/488044

Internet

https://www.karger.com/Article/FullText/488044

Similar Items