7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.

7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.

The cholesterol oxide 7-ketocholesterol (7KCh) has been implicated in numerous age-related diseases such as atherosclerosis, Alzheimer's disease, Parkinson's disease, cancer and age-related macular degeneration. It is formed by the autooxidation of cholesterol and especially cholesterol-fa...

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Bibliographic Details
Main Authors:	Jiahn-Dar Huang, Juan Amaral, Jung Wha Lee, Ignacio R Rodriguez
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4103802?pdf=render

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