Phenobarbital as alternate anticonvulsant for organophosphate‐induced benzodiazepine‐refractory status epilepticus and neuronal injury

Phenobarbital as alternate anticonvulsant for organophosphate‐induced benzodiazepine‐refractory status epilepticus and neuronal injury

Abstract Objective Organophosphates (OPs) such as diisopropylfluorophosphate (DFP) and soman are lethal chemical agents that can produce seizures, refractory status epilepticus (SE), and brain damage. There are few optimal treatments for late or refractory SE. Phenobarbital is a second‐line drug for...

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Bibliographic Details
Main Authors: Doodipala Samba Reddy, Dheepthi Perumal, Victoria Golub, Andy Habib, Ramkumar Kuruba, Xin Wu
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Epilepsia Open
Subjects:
DFP
nerve agents
organophosphate
phenobarbital
status epilepticus
Online Access:https://doi.org/10.1002/epi4.12389

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