Genetic Analysis of NDT80 Family Transcription Factors in Candida albicans Using New CRISPR-Cas9 Approaches

Genetic Analysis of NDT80 Family Transcription Factors in Candida albicans Using New CRISPR-Cas9 Approaches

Transcription factors play key roles in regulating virulence of the human fungal pathogen C. albicans. In addition to regulating the expression of virulence factors, they also control the ability of C. albicans to switch to filamentous hyphal growth, which facilitates biofilm formation on medical de...

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Bibliographic Details
Main Authors: Kyunghun Min, Amy Biermann, Deborah A. Hogan, James B. Konopka
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mSphere
Subjects:
Candida albicans
NDT80
REP1
RON1
hyphae
morphogenesis
Online Access:https://doi.org/10.1128/mSphere.00545-18

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