Simulation-Based Engineering of Humanized Scfv Antibody against hTNF-α
Background: Uncontrolled activity of tumor necrosis factor alpha (TNF-α) as pro-inflammatory cytokine has been linked with pathogenesis of autoimmune/inflammatory diseases. Therefore, modulating of TNF-α associated biological pathways is a promising strategy for alleviating of such diseases. In view...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2020-03-01
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Series: | Pharmaceutical Sciences |
Subjects: | |
Online Access: | https://ps.tbzmed.ac.ir/PDF/Pharm-32975 |