Simulation-Based Engineering of Humanized Scfv Antibody against hTNF-α

Background: Uncontrolled activity of tumor necrosis factor alpha (TNF-α) as pro-inflammatory cytokine has been linked with pathogenesis of autoimmune/inflammatory diseases. Therefore, modulating of TNF-α associated biological pathways is a promising strategy for alleviating of such diseases. In view...

Full description

Bibliographic Details
Main Authors: Maryam Hamzeh-Mivehroud, Ayda Baghal Safarizad, Siavoush Dastmalchi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-03-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:https://ps.tbzmed.ac.ir/PDF/Pharm-32975