The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline

The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline

Sepsis is a dynamic state that progresses at variable rates and has life-threatening consequences. Staging patients along the sepsis timeline requires a thorough knowledge of the evolution of cellular and molecular events at the tissue level. Here, we investigated the kidney, an organ central to the...

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Bibliographic Details
Main Authors: Danielle Janosevic, Jered Myslinski, Thomas W McCarthy, Amy Zollman, Farooq Syed, Xiaoling Xuei, Hongyu Gao, Yun-Long Liu, Kimberly S Collins, Ying-Hua Cheng, Seth Winfree, Tarek M El-Achkar, Bernhard Maier, Ricardo Melo Ferreira, Michael T Eadon, Takashi Hato, Pierre C Dagher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
sepsis
acute kidney injury
single-cell RNA-seq
Online Access:https://elifesciences.org/articles/62270

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