CY-09 Inhibits NLRP3 Inflammasome Activation to Relieve Pain via TRPA1

Peripheral tissue damage leads to inflammatory pain, and inflammatory cytokine releasing is the key factor for inducing the sensitization of nociceptors. As a calcium ion channel, TRPA1 plays an important role in pain and inflammation, thus becoming a new type of anti-inflammatory and analgesic targ...

Full description

Bibliographic Details
Main Authors: Youjia Fan, Gaici Xue, Qianbo Chen, Ye Lu, Rong Dong, Hongbin Yuan
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2021/9806690